PECULIARITIES OF TREATMENT OF MAMMARY GLAND TUMORS IN CATS AND DOGS (OVERVIEW INFORMATION)
Keywords:
breast tumors, dogs, cats, treatment methods, chemotherapy
Abstract
An analysis of literature data related to methods of treatment of mammary gland tumors in dogs and cats was carried out. Despite numerous and many years of research, there is still a need to find effective methods of treatment of oncological pathology. A comprehensive review of current research in this field is important from the point of view of assessing prospects. Treatment is prescribed depending on the type of tumor and the stage of development of the oncological process. This treatment may include surgery, radiation therapy, chemotherapy, immunotherapy, pain relief, and a combination of these methods. Most often, in both dogs and cats, surgical resection is used, the effectiveness of which is influenced by the age and size of the animal, the histological type and size of the tumor, as well as the time between its diagnosis and surgery. At this time, early detection and properly planned surgical intervention play an important role. There are many histological variants of breast tumors with diverse biological behavior. An important factor for increasing the effectiveness of the fight against oncological pathology is early diagnosis. Several classes of chemotherapy drugs are used as primary or adjunctive therapy. Chemotherapy can prolong survival or the period of remission, but is not a radical method. Early tumor detection and correct and timely treatment improves overall survival. Recently, some attention in the field of veterinary oncology began to be paid to targeted therapy and immunotherapy. In particular, interferons are used during various oncological diseases and their effectiveness is studied in clinical trials, including during mammary gland tumors in dogs and cats. Understanding the interaction of neoplasms and the body's immune system is necessary for the rational and effective development of immunotherapy methods for the oncological pathology of mammary gland tumors in dogs and cats.
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3. Ali, M. R. K., Ibrahim, I. M., Ali, H. R., Selim, S. A., & El-Sayed, M. A. (2016). Treatment of natural mammary gland tumors in canines and felines using gold nanorods-assisted plasmonic photothermal therapy to induce tumor apoptosis OPEN ACCESS. International Journal of Nanomedicine, 11, 4849–4863. doi:10.2147/IJN.S109470
4. Alkan, F. Ü., Üstüner, O., Bakırel, T., Çınar, S., Erten, G., & Deniz, G. (2012). The Effects of Piroxicam and Deracoxib on Canine Mammary Tumour Cell Line. ID 976740. doi: 10.1100/2012/976740
5. Amorim, F. V., Souza, H. J. M., Ferreira, A. M. R., & Fonseca, A.B.M. (2006). Clinical, cytological and histopathological evaluation of mammary masses in cats from Rio de Janeiro, Brazil⋆. Journal of Feline Medicine and Surgery, 8(6), 379–388. doi: 10.1016/j.jfms.2006.04.004
6. Anderson, D. (2014). Mammary tumours in the dog and cat (part 2): surgical management. Companion Animal, 19(12). doi: 10.12968/coan.2014.19.12.648
7. Ariyarathna, H., De Silva, N., Aberdein, D., Kodikara, D., Jayasinghe, M., Adikari, R., & Munday, J. S. (2018). Clinicopathological Diversity of Canine Mammary Gland Tumors in Sri Lanka: A One-Year Survey on Cases Presented to Two Veterinary Practices. Veterinary Sciences, 5(2), 46. doi:10.3390/vetsci5020046
8. Atanaskova, P. E., Ilievska, K., Trojacanec, P., Celeska, I., Nikolovski, G., Gjurovski, I., & Dovenski, T., (2014). Canine Mammary Tumours – Clinical Survey. Macedonian Veterinary Review, 37 (2), 129–134. doi:10.14432/j.macvetrev.2014.05.015
9. Augusto, M. (2014). Mammary tumours in the dog and cat: part 1. Companion Animal, 19(9), https://doi.org/10.12968/coan.2014.19.9.448
10. Baptista, C. S., Santos, S., Laso, A., Bastos, E., Ávila, S., Guedes-Pinto, H., Gärtner, F., Gut, I. G., Castrillo, J. L., & Chaves, R. (2012). Sequence variation and mRNA expression of the TWIST1 gene in cats with mammary hyperplasia and neoplasia. The Veterinary Journal, 191(2), 203–207. doi:10.1016/j.tvjl.2011.01.011
11. Bavcar, S., & Argyle, D. J. (2012). Receptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy. Veterinary and Comparative Oncology, 10(3), 163–173. doi: 10.1111/j.1476-5829.2012.00342.x
12. Bely, D. D., Rublenko, M. V., Samoyuluk, V. V., Yevtushenko, I. D., & Maslikov, S. N. (2019). Breast tumour size as a predictor of hemostatic system status and endothelial function in dogs. Regulatory Mechanisms in Biosystems, 10(3), 300–305. doi:10.15421/021946
13. Biller, B., Berg, J., Garrett, L., Ruslander, D., Wearing, R., Abbott, B., Patel, M., Smith, D., Bryan, C. (2016). 2016 AAHA Oncology Guidelines for Dogs and Cats*. Journal of the American Animal Hospital Association, 52 (4): 181–204. doi:10.5326/JAAHA-MS-6570
14. Borrego, J. F., Cartagena, J. C., & Engel, J. (2009). Treatment of feline mammary tumours using chemotherapy, surgery and a COX-2 inhibitor drug (meloxicam): a retrospective study of 23 cases (2002–2007). Veterinary and Comparative Oncology, 7(4), 213–221. doi: 10.1111/j.1476-5829.2009.00194.x
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Published
2024-06-19
How to Cite
SamoilіukV. V., Masyuk, D. D., Sklyarov, P. M., & Lieshova, M. O. (2024). PECULIARITIES OF TREATMENT OF MAMMARY GLAND TUMORS IN CATS AND DOGS (OVERVIEW INFORMATION). Bulletin of Sumy National Agrarian University. The Series: Veterinary Medicine, (1(64), 64-71. https://doi.org/10.32782/bsnau.vet.2024.1.10
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