Detonation synthesis ultrafine suspension of nanodiamonds influence at ewes productivity, lamb growth rate and some biochemical parameters of blood serum
Keywords:
suspension of nanodiamonds, serum, live weight, chemical composition of milk
Abstract
The article highlights the results of 0.005 % and 0.02 % ultra-fine suspension of nanodiamonds introduction effective methods determination and perspectives of using as a possible activator physiological and biochemical status and improvement of the productive qualities of Kharkov interbreed type of Prekos sheep. Implementation of tasks of the work included the use of complex conventional analytical, zootechnical, biochemical, biometric methods. During the previous experiments the chemical composition of ewes’ milk improvement was established, with fat content increasing and a somatic cells significant reduction. In particular, by the content fat content, ewes of the experimental group had a slight advantage of 5.7 % over the representatives of the control group, whereas by the protein content, on the contrary, were inferior – by 13.3 %. The dry matter, dry skim and lactose mass content were almost at the same level. The suspension of nanodiamonds for the young animals provided a slight increase in the growth rate, preservations level and the improvement of the general physiological state. In general, for the period from 20 days to 3 months of age, the suspension of nanodiamonds increased the average daily growth of experimental lambs, which were 10.6–11.3 % higher than the control ones, which led to an increase of live weight during weaning at 6.7 % and 6.9 % against control. In addition, a slight increase of total protein by 2.7 and 8.6 %, albumin – by 2.2 and 3.1 %, gamma globulin – by 5.6 and 1.8 %, A / D ratio – by 9.5 and 13.5 % and glucose – by 1.6 % in serum of young animals of the experimental groups at the end of the experiment in both cases of comparison indicates an increase in blood-forming functions and a certain increase of metabolic processes, which is confirmed by higher body mass. However, these differences were at the trend level. Nanodiamonds suspension administration in various ways (oral and subcutaneous) had no significant difference. In order to further identify the mechanism of the effect of the suspension of nanodiamonds on the sheep organism, a longer test of its use should be conducted with the involvement of larger animal groups and the expansion of a number of physiological studies.
References
1. Akaf'eva, T.I., and Zvezdin. V.N., 2012. Toksikologo-gigienicheskaja ocenka potencial'noj opasnosti dlja zdorov'ja cheloveka nanodispersnogo rastvora dioksida kremnija [Toxicological and hygienic assessment of the potential danger to human health of a nanodispersed solution of silicon dioxide]. Vestnik Permskogo universiteta. Seriya: Biolohiya. issue, 2, pp. 71-74.
2. Rusakova. E.A., Lebedev. S.V., Kvan. O.V., Rahmatullin. Sh.G., Sizova. E.A. and Ulitkina. D.V., 2012. Vlijanie nanorazmernyh chastic zheleza pri intraperitoneal'nom vvedenii na nekotorye biohimicheskie pokazateli krovi zhivotnyh [Influence of nanosized iron particles during intraperitoneal administration on some biochemical parameters of animal blood]. Izvestija Orenburgskogo gosudarstvennogo agrarnogo universiteta. Vol. 33, issue 1-1, pp. 105-106.
3. Galchenko. Ju.P., 2007. Tehnogennye nanochasticy kak neperiodicheskij faktor okruzhajushhej sredy [Technogenic nanoparticles as a non-periodic environmental factor]. Jekologicheskie sistemy i pribory. issue 1, pp. 18-22.
4. Golovin Ju.I., 2014. Nanobiotehnologii [Nanobiotechnology]. Nanoinzhenerija. issue 12 (42), pp. 32-43.
5. Deev S.M. and Lebedenko E.N., 2017. Adresnye bifunkcional'nye belki i gibridnye nanostruktury v diagnostike i terapii raka [Targeted bifunctional proteins and hybrid nanostructures in the diagnosis and treatment of cancer]. Molekuljarnaja biologija. issue 6, pp. 907-926.
6. Bogoslovskaja O.A., Sizova E.A., Poljakova V.S., Miroshnikov S.A., Lejpunskij I.O., Ol'hovskaja I.P. and Glushhenko N.N., 2009. Izuchenie bezopasnosti vvedenija nanochastic medi s razlichnymi fiziko-himicheskimi harakteristikami v organizm zhivotnyh [The study of the safety of the introduction of copper nanoparticles with various physico-chemical characteristics to the animal organism]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 2 (108), pp. 124-127.
7. Korotkova A.M., Lebedev S.V. and Sizova E.A, 2015. Issledovanie mehanizmov razvitija prooksidantnyh jeffektov nanochastic metallov peremennoj valentnosti v teste Triticum Vulgare [Investigation of the development mechanisms of the prooxidant effects of variable-valence metal nanoparticles in the Triticum Vulgare test]. Mezhdunarodnyj nauchno-issledovatel'skij zhurnal. issue 8-3 (39), pp. 14-19.
8. Korotkova A.M., Lebedev S.V. and Sizova E.A., 2015. Uchastie nanochastic nikelja v reguljacii obrazovanija fenol'nyh soedinenij v kletkah Triticum Vulgare [The participation of nickel nanoparticles in the regulation of the formation of phenolic compounds in Triticum Vulgare cells]. In: All-Russian Research Institute of Beef Cattle Breeding, Innovative developments on import substitution in the agri-food sector, Proceedings of the International Conference dedicated to the 85th anniversary of the All-Russian Research Institute of Beef Cattle Breeding. Orenburg, 2015, pp. 3-5.
9. Lebedev S.V. and Gavrish I.A., 2017. Mineral'nyj sostav tkanej Eisenia Fetida v prisutstvii v srede nanochastic oksida molibdena (VI) [The mineral composition of Eisenia Fetida tissues in the presence of molybdenum (VI) oxide nanoparticles in the medium]. Mikrojelementy v medicine. Vol. 18, issue 1, pp. 38-42.
10. Miroshnikov S.A. and Sizova E.A., 2017. Nanomaterialy v zhivotnovodstve (obzor) [Nanomaterials in animal husbandry (review)]. Vestnik mjasnogo skotovodstva. issue 3 (99), pp. 7-22.
11. Notova S.V., Sizova E.A., Kazakova T.V. and Marshinskaja O.V., 2016. Morfobiohimicheskie parametry krys pri vvedenii nanochastic dioksida titana [Morphobiochemical parameters of rats with the introduction of titanium dioxide nanoparticles]. Vestnik mjasnogo skotovodstva. issue 3 (95), pp. 8-14.
12. Korotkova A.M., Lebedev S.V., Kajumov F.G. and Sizova E.A., 2017. Morfofiziologicheskie izmenenija u pshenicy (Triticum VulgareL.) pod vlijaniem nanochastic metallov (Fe, Cu, Ni) i ih oksidov (Fe3O4, CuO, NiO) [Morphophysiological changes in wheat (Triticum VulgareL.) Under the influence of metal nanoparticles (Fe, Cu, Ni) and their oxides (Fe3O4, CuO, NiO)]. Sel'skohozjajstvennaja biologija. Vol. 52, issue1, pp. 172-182.
13. Poljakova V.S., Sizova E.A., Miroshnikov S.A., Notova S.V. and Zavaleeva S.M., 2015. Morfofunkcional'naja harakteristika shhitovidnoj zhelezy pri vvedenii nanochastic medi [Morphological and functional characteristics of the thyroid gland with the introduction of copper nanoparticles]. Morfologija. Vol. 148, issue 6, pp. 54-58.
14. Muruev A.V., Zhapov Zh.N. and Bujantueva D.T., 2010. Nanotehnologii v razvitii zhivotnovodstva [Nanotechnology in the development of livestock]. Vestnik Burjatskoj gosudarstvennoj sel'skohozjajstvennoj akademii im. V.R. Filippova. issue 1, pp. 7-16.
15. Jausheva E.V., Miroshnikov S.A., Kosjan D.B. and Sizova E.A., 2016. Nanochasticy Fe v sochetanii s aminokislotami izmenjajut produktivnye i immunologicheskie pokazateli u cypljat-brojlerov [Fe nanoparticles in combination with amino acids alter productive and immunological parameters in broiler chickens]. Sel'skohozjajstvennaja biologija. Vol. 51, issue 6, pp. 912-920.
16. Zejnalov O.A., Kombarova S.P., Bagrov D.V., Petrosjan M.A., Tolibova G.H., Feofanov A.V. and Shajtan K.V, 2016. O vlijanii nanochastic serebra na fiziologiju zhivyh organizmov [The effect of silver nanoparticles on the physiology of living organisms]. Obzory po klinicheskoj farmakologii i lekarstvennoj terapii. Vol. 14, issue 4, pp. 42-51.
17. Sizova E.A., Miroshnikov S.A., Lebedev S.V., Kudasheva A.V. and Rjabov N.I., 2016 O perspektivnosti nanopreparatov na osnove splavov mikrojelementov-antagonistov (na primere Fe i Co) [On the prospects of nanopreparations based on alloys of trace elements antagonists (for example, Fe and Co)]. Sel'skohozjajstvennaja biologija. Vol. 51, issue 4, pp. 553-562.
18. Orobchenko A.L., Roman'ko M.E. and Kucan A.T., 2014. Jeksperimental'no-teoreticheskoe obosnovanie primenenija nanokompozita metallov (Ag, Cu. Fe i dvuokis' Mn) dlja kur-nesushek pri uslovii hronicheskogo postuplenija s kormom (obobshhenie jeksperi-mental'nyh issledovanij) [Experimental and theoretical justification for the use of metal nanocomposite (Ag, Cu. Fe and Mn dioxide) for laying hens under the condition of chronic feed intake (generalization of experimental studies)]. Veterinarija, zootehnija i biotehnologija. issue 12, pp. 32-40.
19. Nikitin A.Ju., Markova I.V., Lebedev S.V. and Sizova E.A., 2017. Ocenka fiziologo-produktivnogo potenciala cypljat-brojlerov pri chastichnoj zamene zernovoj chasti raciona i vvedenii fermentnyh preparatov v kombikorm [Evaluation of the physiological and productive potential of broiler chickens with partial replacement of the grain portion of the diet and the introduction of enzyme preparations in animal feed]. Vestnik mjasnogo. issue 3 (99), pp. 171-177.
20. Pavlov A.N., 2017. Primenenie nanochastic v agropromyshlennom komplekse i pishhevoj promyshlennosti [The use of nanoparticles in the agricultural sector and the food industry]. In: St. Petersburg, Innovation science as the basis for the development of the modern state, Proceedings of the International Conference, St. Petersburg, 2017, issue. 1, pp. 254-257.
21. Rajkova A.P., 2009. Ispol'zovanie nanoporoshkov metallov dlja predposevnoj obrabotki semjan sel'skohozjajstvennyh kul'tur [The use of metal nanopowders for presowing treatment of seeds of agricultural crops]. Izvestija TSHA. issue 1, pp. 59-65.
22. Sizova E.A, 2017. Vlijanie vkljuchenija v racion nanochastic medi na uroven' kadmija v organizme cypljat-brojlerov [The effect of the inclusion of copper nanoparticles in the diet on the level of cadmium in the body of broiler chickens]. Vestnik mjasnogo. issue 1 (97), pp. 13-20.
23. Sizova E.A., 2012. Morfo-funkcional'nye kriterii optimizacii putej vvedenija nanorazmernyh chastic medi v organizm zhivotnyh [Morphological and functional criteria for optimizing the introduction of nanosized copper particles into animals]. Nauchnoe obozrenie. issue 1, pp. 8-15.
24. Sizova E.A. and Miroshnikov I.S., 2014. Osobennosti obmena himicheskih jelementov v organizme zhivotnyh pri vnutrimy-shechnom vvedenii nanochastic jelementarnogo zheleza [Features of the exchange of chemical elements in animals during intramuscular administration of elemental iron nanoparticles]. Vestnik mjasnogo skotovodstva. issue 3 (86), pp. 80-84.
25. Sizova E.A., Romanova A.P. and Umrihina V.V., 2017. Ispol'zovanie fluktuirujushhej asimmetrii Alburnus Alburnus i Rana Ridibunda dlja ocenki kachestva vodnoj sredy [The use of fluctuating asymmetries of Alburnus Alburnus and Rana Ridibunda to assess the quality of the aquatic environment]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 8 (208), pp. 76-79.
26. Sizova E.A., Tancikuzhina A.A. and Poljakova V.S., 2011. Jekspressija markera apoptoza v kletkah pecheni pri razlichnyh sposobah vvedenija nanochastic medi [Expression of apoptosis marker in liver cells with various methods of introducing copper nanoparticles]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 12 (131), pp. 436-438.
27. Slobodskov A.A., 2014. Vlijanie vnutrimyshechnogo vvedenija nanorazmernyh chastic medi na biohimicheskie pokazateli krovi samok krys pri gestacii [The effect of intramuscular injection of nanosized copper particles on biochemical blood parameters of female rats during gestation]. Sovremennye problemy nauki i obrazovanija. issue 1, p. 328.
28. Nesterov D.V., Sipajlova O.Ju., Sizova E.A. and Shejda E.V., 2014. Sravnitel'naja ocenka vlijanija razlichnyh sposobov vvedenija nanochastic medi na obmen toksichnyh jelementov v myshechnoj tkani cypljat-brojlerov [A comparative assessment of the effect of various methods of introducing copper nanoparticles on the exchange of toxic elements in the muscle tissue of broiler chickens]. Aktual'nye problemy transportnoj mediciny. issue 3 (37), pp. 146-150.
29. Churilov G.I. and Sushilina M.M., 2008. Nanokristalicheskie metally kak jekologicheski chistye mikroudobrenija [Nanocrystalline metals as environmentally friendly microfertilizers]. ,,Jekologicheskoe sostojanie prirodnoj sredy i nauchno-prakticheskie aspekty sovremennyh meliorativnyh tehnologij”. Vestnyk Orenburhskoho hosudarstvennoho unyversyteta. issue 3, pp. 84-86.
30. Notova S.V., Timasheva A.B., Lebedev S.V., Sizova E.A. and Miroshnikov S.V., 2013. Jelementarnyj status i biohimicheskij sostav krovi laboratornyh zhivotnyh pri vnutrimyshechnom vvedenii asparginata i nanochastic medi [The elementary status and biochemical composition of blood of laboratory animals with intramuscular administration of aspartate and copper nanoparticles]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 12 (161), pp. 159-163.
31. Miroshnikova E., Arinzhanov A., Kilyakova Y., Sizova E., Miroshnikov S. Antagonist metal alloy nanoparticles of iron and cobalt: impact on trace element metabolism in carp and chicken. Human and Veterinary Medicine. 2015. Т. 7. № 4, С. 253-259.
32. Pankhurst Q., Connolly J., Jones S. K. and Dobson J. Applications of magnetic nanoparticles in biomedicine. Journal of Physics D: Applied Physics. 2003. № 13, P. 87.
33. Sizova E., Yausheva E., Kosyan D., Miroshnikov S. Growth enhancement by intramuscular injection of elemental iron nano and microparticles. Modern Applied Science. 2015. Т. 9. № 9, С. 17-26.
2. Rusakova. E.A., Lebedev. S.V., Kvan. O.V., Rahmatullin. Sh.G., Sizova. E.A. and Ulitkina. D.V., 2012. Vlijanie nanorazmernyh chastic zheleza pri intraperitoneal'nom vvedenii na nekotorye biohimicheskie pokazateli krovi zhivotnyh [Influence of nanosized iron particles during intraperitoneal administration on some biochemical parameters of animal blood]. Izvestija Orenburgskogo gosudarstvennogo agrarnogo universiteta. Vol. 33, issue 1-1, pp. 105-106.
3. Galchenko. Ju.P., 2007. Tehnogennye nanochasticy kak neperiodicheskij faktor okruzhajushhej sredy [Technogenic nanoparticles as a non-periodic environmental factor]. Jekologicheskie sistemy i pribory. issue 1, pp. 18-22.
4. Golovin Ju.I., 2014. Nanobiotehnologii [Nanobiotechnology]. Nanoinzhenerija. issue 12 (42), pp. 32-43.
5. Deev S.M. and Lebedenko E.N., 2017. Adresnye bifunkcional'nye belki i gibridnye nanostruktury v diagnostike i terapii raka [Targeted bifunctional proteins and hybrid nanostructures in the diagnosis and treatment of cancer]. Molekuljarnaja biologija. issue 6, pp. 907-926.
6. Bogoslovskaja O.A., Sizova E.A., Poljakova V.S., Miroshnikov S.A., Lejpunskij I.O., Ol'hovskaja I.P. and Glushhenko N.N., 2009. Izuchenie bezopasnosti vvedenija nanochastic medi s razlichnymi fiziko-himicheskimi harakteristikami v organizm zhivotnyh [The study of the safety of the introduction of copper nanoparticles with various physico-chemical characteristics to the animal organism]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 2 (108), pp. 124-127.
7. Korotkova A.M., Lebedev S.V. and Sizova E.A, 2015. Issledovanie mehanizmov razvitija prooksidantnyh jeffektov nanochastic metallov peremennoj valentnosti v teste Triticum Vulgare [Investigation of the development mechanisms of the prooxidant effects of variable-valence metal nanoparticles in the Triticum Vulgare test]. Mezhdunarodnyj nauchno-issledovatel'skij zhurnal. issue 8-3 (39), pp. 14-19.
8. Korotkova A.M., Lebedev S.V. and Sizova E.A., 2015. Uchastie nanochastic nikelja v reguljacii obrazovanija fenol'nyh soedinenij v kletkah Triticum Vulgare [The participation of nickel nanoparticles in the regulation of the formation of phenolic compounds in Triticum Vulgare cells]. In: All-Russian Research Institute of Beef Cattle Breeding, Innovative developments on import substitution in the agri-food sector, Proceedings of the International Conference dedicated to the 85th anniversary of the All-Russian Research Institute of Beef Cattle Breeding. Orenburg, 2015, pp. 3-5.
9. Lebedev S.V. and Gavrish I.A., 2017. Mineral'nyj sostav tkanej Eisenia Fetida v prisutstvii v srede nanochastic oksida molibdena (VI) [The mineral composition of Eisenia Fetida tissues in the presence of molybdenum (VI) oxide nanoparticles in the medium]. Mikrojelementy v medicine. Vol. 18, issue 1, pp. 38-42.
10. Miroshnikov S.A. and Sizova E.A., 2017. Nanomaterialy v zhivotnovodstve (obzor) [Nanomaterials in animal husbandry (review)]. Vestnik mjasnogo skotovodstva. issue 3 (99), pp. 7-22.
11. Notova S.V., Sizova E.A., Kazakova T.V. and Marshinskaja O.V., 2016. Morfobiohimicheskie parametry krys pri vvedenii nanochastic dioksida titana [Morphobiochemical parameters of rats with the introduction of titanium dioxide nanoparticles]. Vestnik mjasnogo skotovodstva. issue 3 (95), pp. 8-14.
12. Korotkova A.M., Lebedev S.V., Kajumov F.G. and Sizova E.A., 2017. Morfofiziologicheskie izmenenija u pshenicy (Triticum VulgareL.) pod vlijaniem nanochastic metallov (Fe, Cu, Ni) i ih oksidov (Fe3O4, CuO, NiO) [Morphophysiological changes in wheat (Triticum VulgareL.) Under the influence of metal nanoparticles (Fe, Cu, Ni) and their oxides (Fe3O4, CuO, NiO)]. Sel'skohozjajstvennaja biologija. Vol. 52, issue1, pp. 172-182.
13. Poljakova V.S., Sizova E.A., Miroshnikov S.A., Notova S.V. and Zavaleeva S.M., 2015. Morfofunkcional'naja harakteristika shhitovidnoj zhelezy pri vvedenii nanochastic medi [Morphological and functional characteristics of the thyroid gland with the introduction of copper nanoparticles]. Morfologija. Vol. 148, issue 6, pp. 54-58.
14. Muruev A.V., Zhapov Zh.N. and Bujantueva D.T., 2010. Nanotehnologii v razvitii zhivotnovodstva [Nanotechnology in the development of livestock]. Vestnik Burjatskoj gosudarstvennoj sel'skohozjajstvennoj akademii im. V.R. Filippova. issue 1, pp. 7-16.
15. Jausheva E.V., Miroshnikov S.A., Kosjan D.B. and Sizova E.A., 2016. Nanochasticy Fe v sochetanii s aminokislotami izmenjajut produktivnye i immunologicheskie pokazateli u cypljat-brojlerov [Fe nanoparticles in combination with amino acids alter productive and immunological parameters in broiler chickens]. Sel'skohozjajstvennaja biologija. Vol. 51, issue 6, pp. 912-920.
16. Zejnalov O.A., Kombarova S.P., Bagrov D.V., Petrosjan M.A., Tolibova G.H., Feofanov A.V. and Shajtan K.V, 2016. O vlijanii nanochastic serebra na fiziologiju zhivyh organizmov [The effect of silver nanoparticles on the physiology of living organisms]. Obzory po klinicheskoj farmakologii i lekarstvennoj terapii. Vol. 14, issue 4, pp. 42-51.
17. Sizova E.A., Miroshnikov S.A., Lebedev S.V., Kudasheva A.V. and Rjabov N.I., 2016 O perspektivnosti nanopreparatov na osnove splavov mikrojelementov-antagonistov (na primere Fe i Co) [On the prospects of nanopreparations based on alloys of trace elements antagonists (for example, Fe and Co)]. Sel'skohozjajstvennaja biologija. Vol. 51, issue 4, pp. 553-562.
18. Orobchenko A.L., Roman'ko M.E. and Kucan A.T., 2014. Jeksperimental'no-teoreticheskoe obosnovanie primenenija nanokompozita metallov (Ag, Cu. Fe i dvuokis' Mn) dlja kur-nesushek pri uslovii hronicheskogo postuplenija s kormom (obobshhenie jeksperi-mental'nyh issledovanij) [Experimental and theoretical justification for the use of metal nanocomposite (Ag, Cu. Fe and Mn dioxide) for laying hens under the condition of chronic feed intake (generalization of experimental studies)]. Veterinarija, zootehnija i biotehnologija. issue 12, pp. 32-40.
19. Nikitin A.Ju., Markova I.V., Lebedev S.V. and Sizova E.A., 2017. Ocenka fiziologo-produktivnogo potenciala cypljat-brojlerov pri chastichnoj zamene zernovoj chasti raciona i vvedenii fermentnyh preparatov v kombikorm [Evaluation of the physiological and productive potential of broiler chickens with partial replacement of the grain portion of the diet and the introduction of enzyme preparations in animal feed]. Vestnik mjasnogo. issue 3 (99), pp. 171-177.
20. Pavlov A.N., 2017. Primenenie nanochastic v agropromyshlennom komplekse i pishhevoj promyshlennosti [The use of nanoparticles in the agricultural sector and the food industry]. In: St. Petersburg, Innovation science as the basis for the development of the modern state, Proceedings of the International Conference, St. Petersburg, 2017, issue. 1, pp. 254-257.
21. Rajkova A.P., 2009. Ispol'zovanie nanoporoshkov metallov dlja predposevnoj obrabotki semjan sel'skohozjajstvennyh kul'tur [The use of metal nanopowders for presowing treatment of seeds of agricultural crops]. Izvestija TSHA. issue 1, pp. 59-65.
22. Sizova E.A, 2017. Vlijanie vkljuchenija v racion nanochastic medi na uroven' kadmija v organizme cypljat-brojlerov [The effect of the inclusion of copper nanoparticles in the diet on the level of cadmium in the body of broiler chickens]. Vestnik mjasnogo. issue 1 (97), pp. 13-20.
23. Sizova E.A., 2012. Morfo-funkcional'nye kriterii optimizacii putej vvedenija nanorazmernyh chastic medi v organizm zhivotnyh [Morphological and functional criteria for optimizing the introduction of nanosized copper particles into animals]. Nauchnoe obozrenie. issue 1, pp. 8-15.
24. Sizova E.A. and Miroshnikov I.S., 2014. Osobennosti obmena himicheskih jelementov v organizme zhivotnyh pri vnutrimy-shechnom vvedenii nanochastic jelementarnogo zheleza [Features of the exchange of chemical elements in animals during intramuscular administration of elemental iron nanoparticles]. Vestnik mjasnogo skotovodstva. issue 3 (86), pp. 80-84.
25. Sizova E.A., Romanova A.P. and Umrihina V.V., 2017. Ispol'zovanie fluktuirujushhej asimmetrii Alburnus Alburnus i Rana Ridibunda dlja ocenki kachestva vodnoj sredy [The use of fluctuating asymmetries of Alburnus Alburnus and Rana Ridibunda to assess the quality of the aquatic environment]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 8 (208), pp. 76-79.
26. Sizova E.A., Tancikuzhina A.A. and Poljakova V.S., 2011. Jekspressija markera apoptoza v kletkah pecheni pri razlichnyh sposobah vvedenija nanochastic medi [Expression of apoptosis marker in liver cells with various methods of introducing copper nanoparticles]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 12 (131), pp. 436-438.
27. Slobodskov A.A., 2014. Vlijanie vnutrimyshechnogo vvedenija nanorazmernyh chastic medi na biohimicheskie pokazateli krovi samok krys pri gestacii [The effect of intramuscular injection of nanosized copper particles on biochemical blood parameters of female rats during gestation]. Sovremennye problemy nauki i obrazovanija. issue 1, p. 328.
28. Nesterov D.V., Sipajlova O.Ju., Sizova E.A. and Shejda E.V., 2014. Sravnitel'naja ocenka vlijanija razlichnyh sposobov vvedenija nanochastic medi na obmen toksichnyh jelementov v myshechnoj tkani cypljat-brojlerov [A comparative assessment of the effect of various methods of introducing copper nanoparticles on the exchange of toxic elements in the muscle tissue of broiler chickens]. Aktual'nye problemy transportnoj mediciny. issue 3 (37), pp. 146-150.
29. Churilov G.I. and Sushilina M.M., 2008. Nanokristalicheskie metally kak jekologicheski chistye mikroudobrenija [Nanocrystalline metals as environmentally friendly microfertilizers]. ,,Jekologicheskoe sostojanie prirodnoj sredy i nauchno-prakticheskie aspekty sovremennyh meliorativnyh tehnologij”. Vestnyk Orenburhskoho hosudarstvennoho unyversyteta. issue 3, pp. 84-86.
30. Notova S.V., Timasheva A.B., Lebedev S.V., Sizova E.A. and Miroshnikov S.V., 2013. Jelementarnyj status i biohimicheskij sostav krovi laboratornyh zhivotnyh pri vnutrimyshechnom vvedenii asparginata i nanochastic medi [The elementary status and biochemical composition of blood of laboratory animals with intramuscular administration of aspartate and copper nanoparticles]. Vestnik Orenburgskogo gosudarstvennogo universiteta. issue 12 (161), pp. 159-163.
31. Miroshnikova E., Arinzhanov A., Kilyakova Y., Sizova E., Miroshnikov S. Antagonist metal alloy nanoparticles of iron and cobalt: impact on trace element metabolism in carp and chicken. Human and Veterinary Medicine. 2015. Т. 7. № 4, С. 253-259.
32. Pankhurst Q., Connolly J., Jones S. K. and Dobson J. Applications of magnetic nanoparticles in biomedicine. Journal of Physics D: Applied Physics. 2003. № 13, P. 87.
33. Sizova E., Yausheva E., Kosyan D., Miroshnikov S. Growth enhancement by intramuscular injection of elemental iron nano and microparticles. Modern Applied Science. 2015. Т. 9. № 9, С. 17-26.
Published
2019-07-01
How to Cite
Korkh, I., Pomitun, I., КоsovaN., Boyko, N., Pankiv, L., Ryazanov, P., Ivashchenko, V., & Borodin, V. (2019). Detonation synthesis ultrafine suspension of nanodiamonds influence at ewes productivity, lamb growth rate and some biochemical parameters of blood serum . Bulletin of Sumy National Agrarian University. The Series: Livestock, (1-2(36-37), 58-67. https://doi.org/10.32845/bsnau.lvst.2019.1-2.9
Section
Articles
ISSN 
ISSN 
