DEPENDENCE ON THE GROWTH AND PRODUCTIVITY OF PIGLETS DURING THE SUCCESS PERIOD AND ON THE GROWING PERIOD ON THE ADMINISTRATION OF THE IRON-CONTAINING PRECAUTIONS FEROVITA 200 AND UNIFERON 200
Keywords:
anemia, hemoglobin, maintenance, gains, costs.
Abstract
The article studied the dependence of the hemoglobin content in the blood of piglets before the administration of drugs and on the 28th day of life, the health status of piglets and the level of their mortality in the weaning period and in the rearing period, the survival of piglets before weaning and during rearing, the intensity of their growth before weaning and during rearing on the intramuscular administration of the iron-containing drugs Ferovita 200 and Uniferon 200 on the third day of life of piglets. It was found that the introduction of iron-containing preparations in both groups of piglets on the 28th day of life, compared to the 3rd day of life, caused a probable increase in blood hemoglobin content by 2.16 g/l (29.11%) (р<0.001) in the control group and by 2.93 g/l (39.07%) (р<0.01) in the experimental group. At the same time, the use of the drug Uniferon 200 contributed to increase the haemoglobin content in the blood of the experimental animals by 8.87% or 0.85 g/l 25 days after its administration (р<0.01 compared to the group of animals administered the drug Ferrovita 200 at that time. It was proved that when the drug Uniferon 200 was administered to the animals, there was a tendency to decrease the average daily gains in the post-weaning period by 12.9 g or 5.33%, absolute gains by 0.27 kg or 5.33%, to a reduction of 0.25 kg (5.39%) in the weight of piglets when transferred to growth and of 2.60% in the survival rate of piglets in the postweaning period compared to the analogues injected with Ferovita 200 at that time. It was found that in the group of piglets injected with the drug Ferrovita 200 on the third day of life, all piglets died during the first week of life, mainly diagnosed with hypotrophy, while in the counterparts administered the drug Uniferona 200 during the first week of life, all piglets died in the first week of life, mainly with the diagnosis of hypotrophy, while among the counterparts who were administered the drug Uniferona 200 during this period, only 71.4% died in the first week of life, and the rest in later periods this group had asphyxia. It was found that during the rearing period there was a tendency to increase average daily gains by 2.63%, absolute gains by 0.60 kg (2.65%), weight of piglets at the end of the rearing period by 0.36 kg (1.24%) and improvement in feed conversion by 0.04 kg (2.31%) in the animals injected with the drug Uniferon 200 on the third day of life compared to the animals injected with the drug Ferrovita 200 during this period. It was found that throughout the study period there was a tendency for a slight increase in average daily gains by 1.19%, absolute gains by 0.33 kg and weight of piglets at transfer to fattening by 1.24%, but poorer survival rate of piglets by 3.9% in the group of animals injected with the iron-containing drug Uniferona 200 on the third day after birth compared to the analogs using the drug Ferrovita 200.
References
1. Albers, S. E., Pintens, E. A., Isensee, P. K., Lemanski, C. M., Jang, Y. D. (2022). Effect of Additional Iron Injection to Suckling Pigs on Hematocrit Level during the Suckling Period. Animals, 12, 2980. https://doi.org/10.3390/ani12212980
2. Bhattarai, S., Nielsen, J. P. (2015). Early indicators of iron deficiency in large piglets at weaning. J Swine Health Prod., 23, 10–17. https://www.aasv.org/shap/issues/v23n1/v23n1p10.pdf
3. Chen, X., Zhang, X., Zhao, J., Tang, X., Wang, F., Du, H. (2019). Split iron supplementation is beneficial for newborn piglets. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 120, 109479. https://doi.org/10.1016/j. biopha.2019.109479
4. Clark, S. F. (2009). Iron deficiency anemia: diagnosis and management. Curr Opin Gastroenterol 25, 122–8. https:// doi.org/10.1097/MOG.0b013e32831ef1cd
5. Colby, R. W., Ensminger M. E. (1950). Effect of Vitamin B12 on the Growing Pig, Journal of Animal Science, 9(1), 90–93. https://doi.org/10.2527/jas1950.9190
6. Collard, K. J. (2009). Iron homeostasis in the neonate. Pediatrics, 123, 1208–1216. https://doi.org/10.1542/ peds.2008-1047
7. Csapó, J. E. (1995). Proteins, fats, vitamins and mineral concentration in porcine colostrum and milk from parturion to 60 days. Int Dairy J., 6, 881–902. https://doi.org/10.1016/0958-6946(95)00072-0
8. Derkach, I. (2017). Suchasni tendentsii na vitchyznianomu rynku ferumvmisnykh preparativ dlia tvaryn [Modern trends of the Ukrainian market of ferumcontaining products for animals]. Naukovyi visnyk LNUVMB imeni S.Z. Gzhytskoho [Scientific Messenger LNUVMB], 19(78), 23–25. https://nvlvet.com.ua/index.php/journal/article/download/1289/1288/ (in Ukrainian)
9. Diehl, B., Oster, M., Vernunft, A., Wimmers, K., Bostedt, H. (2022). Intrinsic challenges of neonatal adaptation in swine. Archives animal breeding, 65(4), 427–438. https://doi.org/10.5194/aab-65-427-2022
10. Ding, H., Yu, X., Feng, J. (2020). Iron homeostasis disorder in piglet intestine, Metallomics, 12(10), 1494–1507. https://doi.org/10.1039/d0mt00149j
11. DuKhnitskyi, V., Derkach, I., Derkach, S., Fritsky, I., Plutenko, M., Lozovyi, V., Kostrub, V., Loza, Y., Husak, A. (2021). Hemoglobin content, hematocrit and morphological parameters of blood of piglets under the influence of iron preparations. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 23(101), 8–14. https://doi.org/10.32718/nvlvet10102
12. Egeli, A. K., Farmstadt, T. (1999). An evaluation of iron-dextran supplementation in piglets administered by injection on the first, third or fourth day after birth. Res. Vet. Sci., 66, 179–184. https://doi.org/10.1053/rvsc.1998.0223
13. Fishman, S., Christian, P., West, K. (2000). The role of vitamins in the prevention and control of anaemia. Public Health Nutrition, 3(2), 125–150. https://doi.org/10.1017/S1368980000000173
14. Furugouri, K. (1975). Characteristic Aspects of Iron Metabolism in Piglets. JARQ, 9(3), 171–176. https://www.jircas. go.jp/sites/default/files/publication/jarq/09-3-171-176_0.pdf
15. Heidbüchel, K., Raabe, J., Baldinger, L., Hagmüller, W. Bussemas, R. (2019). One Iron Injection Is Not Enough – Iron Status and Growth of Suckling Piglets on an Organic Farm. Animals, 9, 651. https://doi.org/10.3390/ani9090651
16. Hill, G. M., Link, J. E., Meyer, L., Fritsche, K. L. (1999). Effect of vitamin E and selenium on iron utilization in neonatal pigs. Journal of animal science, 77(7), 1762–1768. https://doi.org/10.2527/1999.7771762x
17. Kegley, E. B., Spears, J. W. , Flowers, W. L. , Schoenherr, W. D. (2002). Fe methionine as a source of Fe for the neonatal pig. Nutr. Res., 22, 1209–1217. https://doi.org/10.1016/S0271-5317(02)00434-7.
18. Kernkamp, H. C. H., Clawson, A. J., Ferneyhough, R. H. (1962). Preventing Iron-Deficiency Anemia in Baby Pigs, Journal of Animal Science, 21(3), 527–532. https://doi.org/10.2527/jas1962.213527x
19. Killip, S., Bennett, M. (2007). Iron Deficiency Anemia. American Family Physician., 75(5), 671–678. https://www. aafp.org/pubs/afp/issues/2007/0301/p671.html 20. Kleinbeck, S., McGlone, J. (1999). Intensive indoor versus outdoor production systems: genotype and supplemental iron effects on blood haemoglobin and selected immune measures in young pigs. J Anim Sci, 77, 2384–2390. https://doi. org/10.2527/1999.7792384x
21. Knight, L. C., Dilger, R. N. (2018). Longitudinal Effects of Iron Deficiency Anemia and Subsequent Repletion on Blood Parameters and the Rate and Composition of Growth in Pigs. Nutrients, 10(5), 632. https://doi.org/10.3390/nu10050632
22. Lemacher, S., Bostedt, H. (1994). Zur Entwicklung der Plasma-Fe-Konzentration und des Hämoglobingehaltes beim Ferkel in den ersten drei Lebenstagen und zur Bedeutung der pränatalen Anämie [The development of plasma iron concentration and hemoglobin content in piglets in the first three days of life and the significance of prenatal anemia]. Tierarztliche Praxis, 22(1), 39–45. https://pubmed.ncbi.nlm.nih.gov/8165659/
23. Lipinski, P., Starzyński, R. R., Canonne-Hergaux, F., Tudek, B., Oliński, R., Kowalczyk, P., Dziaman, T., Thibaudeau, O., Gralak, M. A., Smuda, E., Woliński, J., Usińska, A., Zabielski, R. (2010). Benefits and risks of iron supplementation in anemic neonatal pigs. The American journal of pathology, 177(3), 1233–1243. https://doi.org/10.2353/ ajpath.2010.091020
24. Maes, D., Steyaert, M., Vanderhaeghe, C., López Rodríguez, A., de Jong, E., Del Pozo Sacristán, R., Vangroenweghe, F., Dewulf, J. (2011). Comparison of oral versus parenteral iron supplementation on the health and productivity of piglets. The Veterinary record, 168(7), 188. https://doi.org/10.1136/vr.c7033
25. Merlot, E., Pauwels, M., Hervé, G, Muller, V., Belloc, C., Prunier, A. (2021). Do piglets need iron supplementation in organic farms? Pre-Conference on Animal Husbandry 6-7 September 2021 linked to the 20th Organic World Congress in Rennes, France on 8–10 September. https://orgprints.org/id/eprint/42768/1/2-IAHA_PC2021_paper_iron-piglets_Merlot_e_ LD_v5.pdf
26. Petkov, P. I., Khadzhistoev, V. (1984). Izpolzuvane na dekstrofer-100 i vitamin B12 pri novorodeni praseta [Use of dextrofer-100 and vitamin B12 on newborn pigs]. Veterinarno-meditsinski nauki [Veterinary and medical sciences], 21(5), 71–76. https://pubmed.ncbi.nlm.nih.gov/6474827/ (in Ukrainian)
27. Perri, A. M., Friendship, R. M., Harding, J. C. S., O’Sullivan, T. L. (2016). An investigation of iron deficiency and anemia in piglets and the effect of iron status at weaning on post-weaning performance. J Swine Health Prod., 24, 10–20. https://www.aasv.org/jshap/issues/v24n1/v24n1p10.pdf
28. Peters, J. C., Mahan D. C. (2008). Effects of neonatal Fe status, Fe injections at birth, and weaning in young pigs from sows fed either organic or inorganic trace minerals. J. Anim. Sci., 86, 2261–2269. . https://doi.org/10.2527/ jas.2007-0577.
29. Prokopenko, P. S., Martynov, D. V. (2012). Porivnialna otsinka zastosuvannia zalizovmisnykh preparativ vitchyznianoho ta importnoho vyrobnytstva dlia profilaktyky alimentarnoi anemii porosiat [Comparative evaluation of the use of iron-containing preparations of domestic and imported production for the prevention of alimentary anemia in piglets]. Taurian Scientific Bulletin [Tavriiskyi naukovyi visnyk], 78(2), 209–213. http://www.tnv-agro.ksauniv.ks.ua/archives/78-2-2_2012/48. pdf (in Ukrainian)
30. Pu, Y., Li, S., Xiong, H., Zhang, X., Wang, Y., Du, H. (2018). Iron Promotes Intestinal Development in Neonatal Piglets. Nutrients, 10(6), 726. https://doi.org/10.3390/nu10060726
31. Rincker, M. J., Clarke, S. L., Eisenstein, R. S., Link, J. E., Hill, G. M. (2005). Effects of iron supplementation on binding activity of iron regulatory proteins and the subsequent effect on growth performance and indices of hematological and mineral status of young pigs. J Anim Sci., 83, 2137–2145. https://doi.org/10.2527/2005.8392137x
32. Rydal, M. P., Bhattarai, S., Nielsen, J. P. (2021). An Experimental Model for Iron Deficiency Anemia in Sows and Offspring Induced by Blood Removal during Gestation. Animals: an open access journal from MDPI, 11(10), 2848. https:// doi.org/10.3390/ani11102848
33. Rytych, J. L., Elmore, M. R. P., Burton, M. D., Conrad, M. S., Donovan, S. M., Dilger, R. N. (2012). Early life iron deficiency impairs spatial cognition in neonatal piglets. J. Nutr., 142, 2050–2056. https://doi.org/10.3945/jn.112.165522
34. Sebastian, S., Josef, P., Krawinkel, M. B. (2004). Impact of Feeding High-Iron Rice on Plasma Iron, Hemoglobin and Red Blood Cell Variables of Early-Weaned Piglets: A Pilot Study. Annals of Nutrition & Metabolism, 48(2), 109–117. https://www.jstor.org/stable/48507300
35. Starzyński, R. R., Laarakkers C. M. M., Tjalsma H., Swinkels D. W., Pieszka M., Styś A. (2013). Iron Supplementation in Suckling Piglets: How to Correct Iron Deficiency Anemia without Affecting Plasma Hepcidin Levels. PLoS ONE, 8(5), e64022. https://doi.org/10.1371/journal.pone.0064022
36. Stojanac, N., Stevančević, O., Cincović, M., Belić, B., Plavša, N., Urošević, M. (2016). Effects of Iron Administration Method on Anemia Prevention and Production Performance of Piglets. Acta Scientiae Veterinariae, 44, 1361. https://www. ufrgs.br/actavet/44/PUB%201361.pdf
37. Streyl, K., Carlstron, J., Dantos, E., Mendoza, R., Islas, J. A. T., Bhusha,n C. (2015). Field Evaluation of the Effectiveness of an Oral Toltrazuril and Iron Combination (Baycox® Iron) in Maintaining Weaning Weight by Preventing Coccidiosis and Anaemia in Neonatal Piglets. Parasitol Res., 114(1), 193–200. https://doi.org/10.1007/s00436-015-4525-9
38. Svoboda, M., Vaňhara, J., Berlinská, J. (2017). Parenteral iron administration in suckling piglets – A review. Acta Vet Brno., 86, 249–261. https://doi.org/10.2754/avb201786030249
39. Szudzik, M., Starzyński, R. R., Jończy, A., Mazgaj, R., Lenartowicz, M., Lipiński, P. (2018). Correction: Mateusz, S., et al. Iron Supplementation in Suckling Piglets: An Ostensibly Easy Therapy of Neonatal Iron Deficiency Anemia. Pharmaceuticals 11, 128, Pharmaceuticals (Basel, Switzerland), 12(1), 22. https://doi.org/10.3390/ph12010022
40. Ulizko, S. I., Todorov, M. I. (2014). Retrospektyvnyi ohliad ta suchasnyi stan profilaktyky ta likuvannia anemii u porosiat [Retrospective review and current state of prevention and treatment of anemia in piglets]. Ahrarnyi visnyk Prychornomoria [Agrarian Bulletin of the Black Sea Region], 72, 71–76. http://lib.osau.edu.ua/jspui/bitstream/123456789/1482/1/ avpvet_2014_72_16.pdf (in Ukrainian)
41. Ullrey, D. E., Miller, E. R., West, D. R., Schmidt D. A., Seerley, R. W., Hoefer, J. A., Luecke, R. W. (1959). Oral and Parenteral Administration of Iron in the Prevention and Treatment of Baby Pig Anemia, Journal of Animal Science, 18(1), 256–263. https://doi.org/10.2527/jas1959.181256x
42. Zimmerman, D. R., Speer, V. C., Hays, V. W., Catron, D. V. (1960). A Comparison of Intramuscular and Intraperitoneal Injection of Iron-Dextran, Journal of Animal Science, 19(2), 484–487. https://doi.org/10.2527/jas1960.192484x
43. Wahlstrom, R. C., Juhlm E. W. (1960). A Comparison of Different Methods of Iron Administration on Rate of Gain and Hemoglobin Level of the Baby Pig, Journal of Animal Science, 19(1), 183–188. https://doi.org/10.2527/jas1960.191183x
2. Bhattarai, S., Nielsen, J. P. (2015). Early indicators of iron deficiency in large piglets at weaning. J Swine Health Prod., 23, 10–17. https://www.aasv.org/shap/issues/v23n1/v23n1p10.pdf
3. Chen, X., Zhang, X., Zhao, J., Tang, X., Wang, F., Du, H. (2019). Split iron supplementation is beneficial for newborn piglets. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 120, 109479. https://doi.org/10.1016/j. biopha.2019.109479
4. Clark, S. F. (2009). Iron deficiency anemia: diagnosis and management. Curr Opin Gastroenterol 25, 122–8. https:// doi.org/10.1097/MOG.0b013e32831ef1cd
5. Colby, R. W., Ensminger M. E. (1950). Effect of Vitamin B12 on the Growing Pig, Journal of Animal Science, 9(1), 90–93. https://doi.org/10.2527/jas1950.9190
6. Collard, K. J. (2009). Iron homeostasis in the neonate. Pediatrics, 123, 1208–1216. https://doi.org/10.1542/ peds.2008-1047
7. Csapó, J. E. (1995). Proteins, fats, vitamins and mineral concentration in porcine colostrum and milk from parturion to 60 days. Int Dairy J., 6, 881–902. https://doi.org/10.1016/0958-6946(95)00072-0
8. Derkach, I. (2017). Suchasni tendentsii na vitchyznianomu rynku ferumvmisnykh preparativ dlia tvaryn [Modern trends of the Ukrainian market of ferumcontaining products for animals]. Naukovyi visnyk LNUVMB imeni S.Z. Gzhytskoho [Scientific Messenger LNUVMB], 19(78), 23–25. https://nvlvet.com.ua/index.php/journal/article/download/1289/1288/ (in Ukrainian)
9. Diehl, B., Oster, M., Vernunft, A., Wimmers, K., Bostedt, H. (2022). Intrinsic challenges of neonatal adaptation in swine. Archives animal breeding, 65(4), 427–438. https://doi.org/10.5194/aab-65-427-2022
10. Ding, H., Yu, X., Feng, J. (2020). Iron homeostasis disorder in piglet intestine, Metallomics, 12(10), 1494–1507. https://doi.org/10.1039/d0mt00149j
11. DuKhnitskyi, V., Derkach, I., Derkach, S., Fritsky, I., Plutenko, M., Lozovyi, V., Kostrub, V., Loza, Y., Husak, A. (2021). Hemoglobin content, hematocrit and morphological parameters of blood of piglets under the influence of iron preparations. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 23(101), 8–14. https://doi.org/10.32718/nvlvet10102
12. Egeli, A. K., Farmstadt, T. (1999). An evaluation of iron-dextran supplementation in piglets administered by injection on the first, third or fourth day after birth. Res. Vet. Sci., 66, 179–184. https://doi.org/10.1053/rvsc.1998.0223
13. Fishman, S., Christian, P., West, K. (2000). The role of vitamins in the prevention and control of anaemia. Public Health Nutrition, 3(2), 125–150. https://doi.org/10.1017/S1368980000000173
14. Furugouri, K. (1975). Characteristic Aspects of Iron Metabolism in Piglets. JARQ, 9(3), 171–176. https://www.jircas. go.jp/sites/default/files/publication/jarq/09-3-171-176_0.pdf
15. Heidbüchel, K., Raabe, J., Baldinger, L., Hagmüller, W. Bussemas, R. (2019). One Iron Injection Is Not Enough – Iron Status and Growth of Suckling Piglets on an Organic Farm. Animals, 9, 651. https://doi.org/10.3390/ani9090651
16. Hill, G. M., Link, J. E., Meyer, L., Fritsche, K. L. (1999). Effect of vitamin E and selenium on iron utilization in neonatal pigs. Journal of animal science, 77(7), 1762–1768. https://doi.org/10.2527/1999.7771762x
17. Kegley, E. B., Spears, J. W. , Flowers, W. L. , Schoenherr, W. D. (2002). Fe methionine as a source of Fe for the neonatal pig. Nutr. Res., 22, 1209–1217. https://doi.org/10.1016/S0271-5317(02)00434-7.
18. Kernkamp, H. C. H., Clawson, A. J., Ferneyhough, R. H. (1962). Preventing Iron-Deficiency Anemia in Baby Pigs, Journal of Animal Science, 21(3), 527–532. https://doi.org/10.2527/jas1962.213527x
19. Killip, S., Bennett, M. (2007). Iron Deficiency Anemia. American Family Physician., 75(5), 671–678. https://www. aafp.org/pubs/afp/issues/2007/0301/p671.html 20. Kleinbeck, S., McGlone, J. (1999). Intensive indoor versus outdoor production systems: genotype and supplemental iron effects on blood haemoglobin and selected immune measures in young pigs. J Anim Sci, 77, 2384–2390. https://doi. org/10.2527/1999.7792384x
21. Knight, L. C., Dilger, R. N. (2018). Longitudinal Effects of Iron Deficiency Anemia and Subsequent Repletion on Blood Parameters and the Rate and Composition of Growth in Pigs. Nutrients, 10(5), 632. https://doi.org/10.3390/nu10050632
22. Lemacher, S., Bostedt, H. (1994). Zur Entwicklung der Plasma-Fe-Konzentration und des Hämoglobingehaltes beim Ferkel in den ersten drei Lebenstagen und zur Bedeutung der pränatalen Anämie [The development of plasma iron concentration and hemoglobin content in piglets in the first three days of life and the significance of prenatal anemia]. Tierarztliche Praxis, 22(1), 39–45. https://pubmed.ncbi.nlm.nih.gov/8165659/
23. Lipinski, P., Starzyński, R. R., Canonne-Hergaux, F., Tudek, B., Oliński, R., Kowalczyk, P., Dziaman, T., Thibaudeau, O., Gralak, M. A., Smuda, E., Woliński, J., Usińska, A., Zabielski, R. (2010). Benefits and risks of iron supplementation in anemic neonatal pigs. The American journal of pathology, 177(3), 1233–1243. https://doi.org/10.2353/ ajpath.2010.091020
24. Maes, D., Steyaert, M., Vanderhaeghe, C., López Rodríguez, A., de Jong, E., Del Pozo Sacristán, R., Vangroenweghe, F., Dewulf, J. (2011). Comparison of oral versus parenteral iron supplementation on the health and productivity of piglets. The Veterinary record, 168(7), 188. https://doi.org/10.1136/vr.c7033
25. Merlot, E., Pauwels, M., Hervé, G, Muller, V., Belloc, C., Prunier, A. (2021). Do piglets need iron supplementation in organic farms? Pre-Conference on Animal Husbandry 6-7 September 2021 linked to the 20th Organic World Congress in Rennes, France on 8–10 September. https://orgprints.org/id/eprint/42768/1/2-IAHA_PC2021_paper_iron-piglets_Merlot_e_ LD_v5.pdf
26. Petkov, P. I., Khadzhistoev, V. (1984). Izpolzuvane na dekstrofer-100 i vitamin B12 pri novorodeni praseta [Use of dextrofer-100 and vitamin B12 on newborn pigs]. Veterinarno-meditsinski nauki [Veterinary and medical sciences], 21(5), 71–76. https://pubmed.ncbi.nlm.nih.gov/6474827/ (in Ukrainian)
27. Perri, A. M., Friendship, R. M., Harding, J. C. S., O’Sullivan, T. L. (2016). An investigation of iron deficiency and anemia in piglets and the effect of iron status at weaning on post-weaning performance. J Swine Health Prod., 24, 10–20. https://www.aasv.org/jshap/issues/v24n1/v24n1p10.pdf
28. Peters, J. C., Mahan D. C. (2008). Effects of neonatal Fe status, Fe injections at birth, and weaning in young pigs from sows fed either organic or inorganic trace minerals. J. Anim. Sci., 86, 2261–2269. . https://doi.org/10.2527/ jas.2007-0577.
29. Prokopenko, P. S., Martynov, D. V. (2012). Porivnialna otsinka zastosuvannia zalizovmisnykh preparativ vitchyznianoho ta importnoho vyrobnytstva dlia profilaktyky alimentarnoi anemii porosiat [Comparative evaluation of the use of iron-containing preparations of domestic and imported production for the prevention of alimentary anemia in piglets]. Taurian Scientific Bulletin [Tavriiskyi naukovyi visnyk], 78(2), 209–213. http://www.tnv-agro.ksauniv.ks.ua/archives/78-2-2_2012/48. pdf (in Ukrainian)
30. Pu, Y., Li, S., Xiong, H., Zhang, X., Wang, Y., Du, H. (2018). Iron Promotes Intestinal Development in Neonatal Piglets. Nutrients, 10(6), 726. https://doi.org/10.3390/nu10060726
31. Rincker, M. J., Clarke, S. L., Eisenstein, R. S., Link, J. E., Hill, G. M. (2005). Effects of iron supplementation on binding activity of iron regulatory proteins and the subsequent effect on growth performance and indices of hematological and mineral status of young pigs. J Anim Sci., 83, 2137–2145. https://doi.org/10.2527/2005.8392137x
32. Rydal, M. P., Bhattarai, S., Nielsen, J. P. (2021). An Experimental Model for Iron Deficiency Anemia in Sows and Offspring Induced by Blood Removal during Gestation. Animals: an open access journal from MDPI, 11(10), 2848. https:// doi.org/10.3390/ani11102848
33. Rytych, J. L., Elmore, M. R. P., Burton, M. D., Conrad, M. S., Donovan, S. M., Dilger, R. N. (2012). Early life iron deficiency impairs spatial cognition in neonatal piglets. J. Nutr., 142, 2050–2056. https://doi.org/10.3945/jn.112.165522
34. Sebastian, S., Josef, P., Krawinkel, M. B. (2004). Impact of Feeding High-Iron Rice on Plasma Iron, Hemoglobin and Red Blood Cell Variables of Early-Weaned Piglets: A Pilot Study. Annals of Nutrition & Metabolism, 48(2), 109–117. https://www.jstor.org/stable/48507300
35. Starzyński, R. R., Laarakkers C. M. M., Tjalsma H., Swinkels D. W., Pieszka M., Styś A. (2013). Iron Supplementation in Suckling Piglets: How to Correct Iron Deficiency Anemia without Affecting Plasma Hepcidin Levels. PLoS ONE, 8(5), e64022. https://doi.org/10.1371/journal.pone.0064022
36. Stojanac, N., Stevančević, O., Cincović, M., Belić, B., Plavša, N., Urošević, M. (2016). Effects of Iron Administration Method on Anemia Prevention and Production Performance of Piglets. Acta Scientiae Veterinariae, 44, 1361. https://www. ufrgs.br/actavet/44/PUB%201361.pdf
37. Streyl, K., Carlstron, J., Dantos, E., Mendoza, R., Islas, J. A. T., Bhusha,n C. (2015). Field Evaluation of the Effectiveness of an Oral Toltrazuril and Iron Combination (Baycox® Iron) in Maintaining Weaning Weight by Preventing Coccidiosis and Anaemia in Neonatal Piglets. Parasitol Res., 114(1), 193–200. https://doi.org/10.1007/s00436-015-4525-9
38. Svoboda, M., Vaňhara, J., Berlinská, J. (2017). Parenteral iron administration in suckling piglets – A review. Acta Vet Brno., 86, 249–261. https://doi.org/10.2754/avb201786030249
39. Szudzik, M., Starzyński, R. R., Jończy, A., Mazgaj, R., Lenartowicz, M., Lipiński, P. (2018). Correction: Mateusz, S., et al. Iron Supplementation in Suckling Piglets: An Ostensibly Easy Therapy of Neonatal Iron Deficiency Anemia. Pharmaceuticals 11, 128, Pharmaceuticals (Basel, Switzerland), 12(1), 22. https://doi.org/10.3390/ph12010022
40. Ulizko, S. I., Todorov, M. I. (2014). Retrospektyvnyi ohliad ta suchasnyi stan profilaktyky ta likuvannia anemii u porosiat [Retrospective review and current state of prevention and treatment of anemia in piglets]. Ahrarnyi visnyk Prychornomoria [Agrarian Bulletin of the Black Sea Region], 72, 71–76. http://lib.osau.edu.ua/jspui/bitstream/123456789/1482/1/ avpvet_2014_72_16.pdf (in Ukrainian)
41. Ullrey, D. E., Miller, E. R., West, D. R., Schmidt D. A., Seerley, R. W., Hoefer, J. A., Luecke, R. W. (1959). Oral and Parenteral Administration of Iron in the Prevention and Treatment of Baby Pig Anemia, Journal of Animal Science, 18(1), 256–263. https://doi.org/10.2527/jas1959.181256x
42. Zimmerman, D. R., Speer, V. C., Hays, V. W., Catron, D. V. (1960). A Comparison of Intramuscular and Intraperitoneal Injection of Iron-Dextran, Journal of Animal Science, 19(2), 484–487. https://doi.org/10.2527/jas1960.192484x
43. Wahlstrom, R. C., Juhlm E. W. (1960). A Comparison of Different Methods of Iron Administration on Rate of Gain and Hemoglobin Level of the Baby Pig, Journal of Animal Science, 19(1), 183–188. https://doi.org/10.2527/jas1960.191183x
Published
2023-10-31
How to Cite
Povod, M. H., Mykhalko, O. H., Hutyi, B. V., Lumedze, T. S.-M., Lumedze, T. S.-M., Verbelchuk, T. V., & Moisei, I. S. (2023). DEPENDENCE ON THE GROWTH AND PRODUCTIVITY OF PIGLETS DURING THE SUCCESS PERIOD AND ON THE GROWING PERIOD ON THE ADMINISTRATION OF THE IRON-CONTAINING PRECAUTIONS FEROVITA 200 AND UNIFERON 200. Bulletin of Sumy National Agrarian University. The Series: Livestock, (3), 40-49. https://doi.org/10.32782/bsnau.lvst.2023.3.6
Section
Articles
ISSN 
ISSN 
