PATHOLOGY OF THE CARDIOVASCULAR SYSTEM OF TURKEYS
Abstract
The work is devoted to the current problem of industrial turkey farming, One of the aspects of the pathology of the cardiovascular system ̶ ruptures of arterial vessels (laterism) in heavy cross turkeys in the final fattening period. The literature review presents the study of this issue in the global practice of industrial turkey farming. The most established etiological factors that cause this pathology in turkeys and instructions for the prevention of the disease are described. The aim of the work was to conduct a pathological and pathomorphological evaluation of problem areas of turkeys regarding the occurrence of laterism under the conditions of a balanced diet and feeding of copper chelates, aimed at improving the morphological state of the birds' vessels. 67 cadavers of male turkeys older than 13 weeks of the Converter cross that died of sudden death due to vascular ruptures were subjected to pathological examination. The general condition of the bird on the day of death, age, sex, pathological (primary and concurrent) factors that led to death, location of vascular rupture were evaluated. Pathological material was selected for pathohistological studies. Poultry diet was assessed for balance in nutritional ingredients, vitamins, macro-microelements according to age, sex, breed and fattening period. As a result of the research, it was established that despite the use of copper chelating compounds, cases of sudden death due to laterism are registered in male turkeys older than 13 weeks. The most common occurrence of laterism are the cranial renal (a.renalis cranialis) and caudal mesenteric (a. mesenterica caudalis) arteries from the thoraco-abdominal aorta. Lesions of the coronary arteries, capable of causing hemorrhages, were not detected in any of the examined corpses of Converter cross turkeys. Among the pathologies secondary to laterism, we detected localized or diffuse degenerative changes in the myocardium, as well as stagnantion processes were in individual systemic circulation vessels within in the liver and lungs. Stagnant hyperemia in the vessels of the venous system led to degenerative and inflammatory lesions within their membranes, resulting in effusion into the surrounding vascular space, damage to the endothelium, swelling of the elastic and collagen fibers in the median membrane with macrophagic proliferation.
References
2. Carlton, W.W. & Henderson, W. (1963). Cardiovascular lesions in experimental copper deficiency in chickens. Journal of Nutrition , 81: 200 -208.
3. Cheville, N.F. (1994). Extracellular substances, pigments, and crystals. In Ultrastructural Pathology, An Introduction to Interpretation (pp. 277 -283). Ames: Iowa State University Press.
4. Coulson, W.F., Linker, A. & Bottcher, A. (1969). Lathyrism in swine.Archives in Pathology, 87:411- 417.
5. Crespo, R. & Shivaprasad, H.L. (2003). Developmental, metabolic, and other noninfectious disorders. In Y.M. Saif (Ed.), Diseases of Poultry, 11th edn (pp. 1055 -1102). Ames: Iowa State Press.
6. Doane, F.W. & Anderson, N. (1987). Electron Microscopy and Diagnostic Virology. A Practical Guide and Atlas (pp.4-27). Cambridge: Cambridge University Press.
7. Environmental Protection Agency (1991). Determination of Metals in Fish Tissue by Inductively-Coupled Plasma Atomic Emission Spectro- metry Revision 2.1, method 200.11 (pp. 178 -209). Washington, DC: US Environmental Protection Agency, Office of Research and Development, Environmental Monitoring and Support Laboratory.
8. Galey, F.D., Slenning, B.D., Anderson, M.L., Breneman, P.C., Littlefield, E.S., Melton, L.A. & Tracy, M.L. (1990). Lead concentrations in blood and milk from periparturient dairy heifers seven months after an episode of acute lead toxicity. Journal of Veterinary Diagnostic Investigation , 2 : 222 -226.
9. Graham, C.L.G. (1977). Copper levels in livers of turkeys with naturally occurring aortic rupture. Avian Diseases , 21 :113 -116.
10. Julian R.J.(1996) ed. C.Riddell [2nd. ed.].Cardiovascular system.Am. Assoc. Avian Pathologist, Kennett Squre,PA. Avian Histopatology. 10: 69-88.
11. Krista, L.,Waibel P., Shofner A. et al (1967). Natural Dissecting Aunerism (Aortic Repture)and blood Pressure in the Turkey. Nature,:1162-1163.doi.org/10`1038/2141162a 0
12. Krista, L.M., McDaniel, G.R., Mora, E.C., Patterson, R. & Whitesides,J.F. (1987). Histological evaluation of the vascular system for the severity of atherosclerosis in hyper and hypotensive male and female turkeys: Comparison between young and aged turkeys. Poultry Science , 66 :1033 -1044.
13. Krista, L.M. & McQuire, J.A. (1988). Atherosclerosis in coronary, aortic, and sciatic arteries from wild male turkeys (Meleagridis gallopava silvestris ). American Journal of Veterinary Research , 49 :1582 -1588.
14. McMurray, C.H. & Blanchflower, W.J. (1979). Application of a high- performance liquid chromatography fluorescence method for the rapid determination of alpha-tocopherol in the plasma of cattle and pigs and its comparison with direct fluorescence and high-performance liquid chromatography-ultraviolet detection methods. Journal of Chromatography, 178: 525-531.
15. Middleton, C.C. (1965). Naturally occurring atherosclerosis in broad- breasted bronze turkeys. In Comparative Atherosclerosis (pp. 59- 61). New York: Harper and Row.
16. Miller, K.W., Lorr, N.A. & Yang, C.S. (1984). Simultaneous determina- tion of plasma retinol, alpha-tocopherol, lycopene, alpha-carotene, and beta-carotene by high-performance liquid chromatography. Analytical Biochemistry,138 : 340 −345.
17. Mushabbar,S. & Lesch,M. (1997). Coronary artery aneurysm: a review.Progress in Cardiovascular Diseases, 40 :77 – 84.
18. Nickel, R., Schummer, A. & Seiferle, E. (1977). Circulatory sytem. In Anatomy of the domestic birds (pp. 90 -91). New York: Springer- Verlag.
19. O’Dell, B.L., Hardwick, B.C., Reynolds, G. & Savage, J.E. (1961). Connective tissue defect in the chick resulting from copper deficiency. Proceedings of Society for Experimental Biology and Medicine , 108 : 402 – 405.
20. O`Grady M.R. & O`Sullivan (2004).Dilated cardiomiopathy: An update. Vet. Clin. Nort. Am. Small anim. pract.V.34:1187 -1207.
21. Owles, J.P. (1984). Identification of monensin, narasin, salinomycin and lasalocid in pre-mixes and feeds by thinlayer chromatography. Analyst ,109 :1331-1333.
22. Peckham, M.C. (1984). Miscellaneous diseases and conditions. In M.S. Hofstad (Ed.). Diseases of Poultry, 8th edn (pp. 766-767). Ames: Iowa State University Press.
23. Pons, W.A., Jr. & Hoffpauir, C.L. (1957). Determination of free and total gossypol in mixed feeds containing cottonseed meals. Journal of Association of Official Agricultural Chemists , 40 , 1068 −1080.
24. Potter, K.A. & Besser, T.A. (1994). Cardiovascular lesions in Bovine Marfan Syndrome. Veterinary Pathology, 31 : 501 – 509.
25. Pritchard, W.R., Henderson, W. & Beall, C.W. (1958). Experimental production of dissecting aneurysm in turkeys. American Journal of Veterinary Research , 19 : 696-705.
26. Puls, R. (1994a). Copper. In Mineral Levels in Animal Health , 2nd edn (pp. 101-103). Clearbrook: Sherpa International.
27. Puls, R. (1994b). Zinc. In Mineral Levels in Animal Health , 2nd edn (pp. 294 -296). Clearbrook: Sherpa International.
28. Robinson, W.F. & Maxie, M.G. (1993). The cardiovascular system. In K.V.F. Jubb (Ed.), Pathology of Domestic animals , 4th edn (pp. 1-100). New York: Academic Press.
29. Rottinghaus, G.E., Olesen, B. & Osweiler, G.D. (1982). Rapid screening method for aflatoxin B, zearalenone, ochratoxin A, T-2 toxin, diacetoxyscirpenol and vomitoxin. Proceedings of the 25th AnnualMeeting of the American Association of Veterinary Laboratory Diagnositicians , 25 :477 – 484.
30. Savage, J.E., Bird, D.W., Reynolds, G. & O’Dell, B.L (1966). Comparison of copper deficiency and lathyrism in turkey poults. Journal of Nutrition, 88: 15-25.
31. Shivaprasad H.L., Crespo R. & Pushner B. (2004). Coronary artery ruptyre in mail commercial turkeys. Avian Patology.V.33:226-232.
32. Senne, D.A (1998). Virus propagation in embryonating eggs. In D.E. Swayne (Ed.), A Laboratory Manual for the Isolation and identification of Avian Pathogens, 4th edn (pp. 235-240). Kennett Square, PA: American Association of Avian Pathologists.
33. Simpson, C.F., Boucek, R.J.& Noble,N.L. (1980). Similarity of aortic pathology in Marfan’s syndrome, copper deficiency in chicks, and b- aminoproprionitrile toxicity in turkeys. Experimental Molecular Pathology, 32 : 81- 90.
34. Thayer, S.G. & Beard, C.W. (1998). Serologic procedures. In D.E. Swayne (Ed.), A Laboratory Manual for the Isolation and Identificaion of Avian Pathogens, 4th edn (pp. 255-266). Kennett Square, PA: American Association of Avian Pathologists.
35. Tracy, M.L. & Moeller, G. (1990). Continuous flow vapor generation for inductively coupled argon plasma spectrometric analysis. Part 1: selenium. Journal of Association of Official Analytical Chemists , 3: 404 – 410.
36. van der Linde-Sipman, J.S., Kroneman, J., Meulenaar, H. & Vos, J.H. (1985). Necrosis and rupture of the aorta and pulmonary trunk in four horses. Veterinary Pathology, 22 :51-53.
37. Vanhooser, S.L., Stair, E., Edwards, W.C., Labor, M.R. & Carter, D. (1994). Aortic rupture in ostrich associated with copper deficiency. Veterinary and Human Toxicology, 36 : 225-226.
38. Vink-Nooteboom, M., Schoemaker, N.J., Kik, M.L.J., Lumeij, J.T. & Wolvekamp, W.Th.C. (1998). Clinical diagnosis of aneurysm of the right coronary artery in a white cockatoo (Cacatua alba ). Journal of Small Animal Practice , 39 : 533 -537.
39. Waibel, P.E. & Pomeroy, B.S. (1958). Studies on the production of aortic hemorrhage in growing turkeys with Beta-aminoproprionitirile. Poultry Science , 37: 934 – 938.
40. Welz, B. & Melcher, M. (1985). Decomposition of marine biological tissues for determination of arsenic, selenium and mercury using hydride generation and cold-vapor atomic absorption spectrometers. Analytical Chemistry, 57: 427 – 431.