Antianemic effect of preparations of iron in pigs
Abstract
Anemia is one of the most common non-communicable diseases of newborn mammals. In modern conditions of pig breeding an important task, which does not lose relevance, is to provide the needs of newborn piglets in Iron. Modern prevention of iron deficiency anemia and pharmacotherapy for this pathology are based primarily on intramuscular administration of iron dextran drugs to piglets.
The article presents the results of studies of antianemic action in the body of piglets Iron in the form of clatrochelate and in rare unconventional valence IV. The study was performed on analogous piglets, which were divided into two groups – control and experimental. Piglets from the experimental group were selected from sows given 10 ml of 10% Iron(IV) clatrochelate solution twice intramuscularly during pregnancy. Piglets of the control group according to the traditional scheme of prevention of iron deficiency anemia on the second day of life were administered iron dextran drug in a dose of 2 ml for the animal. The material for the research was the body weight and blood serum of piglets. The experiment lasted 60 days.
The results of the studies showed the absence of death and anemia among the piglets of the experimental group, the high intensity of their growth, which indicates the prophylactic effect of Iron(IV) clatrochelate used in pregnant sows. It was found that the body weight of piglets in the experimental group did not differ from the body weight of piglets in the control group; was less than 5 days of their life and exceeded in all subsequent periods of cultivation, up to weaning.
It is known that the study of the content of iron in the serum is important for screening, diagnosis of iron deficiency anemia and to assess the effectiveness of treatment of patients with iron deficiency anemia. Therefore, one of the tasks of our study was to determine the content of iron in the serum of piglets under the influence of various iron-containing drugs. The lower content of iron in the serum of piglets of the experimental group than in the control up to 12 days of age, due to the peculiarities of its pharmacokinetics – the effect of the placental barrier.
The content of copper in the serum of piglets of the experimental and control groups was almost the same during the experimental period and was within physiological values.
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