THE EFFECTS OF COMPLEX TREATMENT ON THE ORGANISM OF CATS UNDER OTODECTOSIS
Abstract
Studies of O. Cenotis infested cats showed that on the 10th day of treatment, the indicator of infestation decreased by 17,8 ± 0,92 tо 2,1 ± 0,21 ticks in a swab, and on the 20th day live ticks were not found. For the treatment of cats with Otodectosis, a complex treatment included Dectomax, 25% wax moth larvae extract and sulfur-tar liniment with wax moth larvae additive. The result was the same for the animals of the 1st and 2nd experimental groups, where Dectomax showed 100% effectiveness against pathogens of Otodectosis, and the means of symptomatic therapy did not affect its acaricidal effect. Clinical examination of patients showed that in the cats of the 1st group, itching and soreness in the ear area disappeared on average on the 8th day of treatment, cessation of exudation was noted on the 11th day, the skin lesions were completely healed on the 15th day, and the redness of the inner surface of the auricles disappeared on the 19th day. When using preparations containing wax moth larvae (animals of the 2nd group), it was possible to achieve similar results already on the 5th, 8th,10th and 14th days, respectively. Observing the content of leukocytes in the blood of the experimental cats, we found that in the animals that used Dectomax and sulfur-tar liniment, on the 10th day after the beginning of treatment, this indicator increased by 2.8% compared to the analogue before treatment (22,40±0,82 and 21,80±0,87 G/l), respectively. The results of the blood leukogram studies of the experimental animals before the withdrawal and on the 10th day of the experiment showed that the content of basophils decreased from 6,30±0,15 tо 3,30±0,12%, eosinophils from 21,80±0,87 tо 20,40±0,56%, respectively , but at the same time the apperarance of young neutrophils was noted – 1,4±0,09%. When using a complex treatment including Dectomax, wax moth larvae extract 25% and sulfur-tar liniment with the addition of wax moth larvae to cats with Otodectosis, the results of the morphological examination of the blood indicated the fading of the inflammatory and allergic processes in the body, despite of the release of a significant amount of pathogen toxins. On the 10th day, it was possible to achieve a decrease in the number of leukocytes from 22,40±0,82 tо 17,20±0,53 G/l (by 23,2%, Р < 0,001), including eosinophils – from 20,40±0,56 tо±13,30±0,42 % (by 34,8%, Р <0,01), rod-shaped neutrophils – from 7,60±0,29 tо 6,20±0,24 % (by 18,4%, Р <0,001) , as well as of young neutrophils, compared to the indicators of the animals that received only Dectomax and sulfur-tar liniment. An increase in the content of segmental neutrophils in the leukogram of cats under the combination of medical products with preparations of wax moth larvae from 38,60±2,87 tо 49,10±2,08% (by 27,5%, Р<0,01), was detected due to the decrease in the number of leukocytes of other types. The results of studies of biochemical indicators of blood under Otodectosis, with various methods of treatment, confirmed the stimulating effect of preparations containing wax moth larvae, which speed up the reparative processes in the cat’s organism during the recovery time.
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